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Age Reversal in Singapore: Activating Longevity Genes with Cutting-Edge Science

Updated: Aug 13

Dr. David Sinclair's Anti-Aging Protocol


Singapore's Aging Crisis  

With 25% of the population projected to be over 65 by 2030 (MSF 2023), biological age reduction has become a national priority. Our clinic adapts Dr. Sinclair's Harvard research for tropical urban living.


The Epigenetic Breakthrough  

Sinclair's work shows we can influence:  

- Sirtuin activation (NAD+-dependent longevity proteins)  

- mTOR regulation (cellular recycling pathway)  

- AMPK stimulation (energy sensing enzyme) 


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The 3-Pillar Protocol  


1. Hyperbaric Oxygen Therapy (HBOT)  

- 90-minute sessions at 1.5 ATA  

- Increases stem cell production by 800% (Aging 2020)  

- Our Orchard clinic features Singapore's first multi-person HBOT chamber  


2. Time-Restricted Nutrition  

- 16-hour fasting window (8PM-12PM)  

- Key supplements:  

  - NMN (500mg/day) - increases NAD+ by 40%  

  - Trans-resveratrol (1g with fats) - activates SIRT1  

  - Spermidine (10mg) - enhances autophagy  


3. Metabolic Stress Cycling  

- Weekly high-intensity training (VO2 max intervals)  

- Monthly 36-hour fasts with electrolyte support  

- Sauna/cold plunge contrast therapy  


Local Adaptations  

- Modified fasting protocols for hawker center diets  

- Heat-acclimated workout regimens  

- Pollution-defense nutraceuticals (broccoli sprout extract)  


Client Results at 6 Months  

- Average 5.2 year reduction in epigenetic age  

- 28% improvement in mitochondrial function  

- 17% increase in telomere length (qPCR tested)


 
 
 

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